The Single-cell Pediatric Cancer Atlas (ScPCA) Portal is now accepting dataset submissions!

May 15, 2023

Update: As of September 2023, we are no longer accepting contributions.

Interested in contributing data to the ScPCA Portal? Sign up to be notified about future opportunities!

In 2019, Alex’s Lemonade Stand Foundation (ALSF) established the Single-cell Pediatric Cancer Atlas (ScPCA) through awards for data generation and to create an atlas of single-cell gene expression profiles of pediatric cancers of different types and from different organ sites. The Data Lab launched the ScPCA Portal in 2022 to make uniformly processed, summarized single-cell and single-nuclei RNA-seq data and de-identified metadata available for download. The ScPCA Portal also supports other data modalities, such as bulk RNA-seq, CITE-seq, and spatial transcriptomics. The ScPCA Portal currently hosts data for over 500 pediatric tumor and patient-derived xenograft samples from more than 50 cancer types, and continues to grow.

Call for Contributions to ScPCA

The Data Lab is seeking contributions to the ScPCA Portal from researchers with existing single-cell datasets. We are now accepting submissions of 10x Genomics single-cell or single-nuclei profiling of childhood and adolescent cancer (ages 0-19) data, broadly defined to include relevant animal models, patient-derived xenografts, or cell lines, as well as tumor data.

Eligible datasets will be made publicly available on the ScPCA Portal. Over 100 users have already downloaded datasets from the portal since it was launched last year! Openly sharing your data can increase the impact of your research, enhance the visibility of your work, and lead to more reproducible research. Researchers that submit data may also be eligible to receive a small one-time grant of unrestricted funds to be used for childhood cancer research.

Eligible researchers must:

To learn more, view the full guidelines for contributing a dataset to the ScPCA Portal.

Support for Potential Contributors

ALSF and the Data Lab look forward to supporting potential contributors through the process of submitting their dataset. 

Awards for Eligible Researchers

Up to 10 eligible researchers will receive $5000 in unrestricted funds. Once an eligible single-cell dataset submission has been completed and approved by the Data Lab, researchers will be invited to complete a grant application for the unrestricted funds consisting of basic contact and payment information. Eligibility will be determined at ALSF’s discretion. Funds are available on a first-come-first-served basis and distributed to the researcher’s institution, which must be a non-profit institution. ALSF does not allow any funds to be used for research utilizing human embryonic stem cells or nonhuman primates. Research with human induced pluripotent stem cells is permissible.

Guidance from the Data Lab

Contributing data to the ScPCA Portal requires potential submitters to generate summarized gene expression data for their samples using the Data Lab’s existing pipeline, which must be completed by September 1, 2023. The Data Lab team is available to provide guidance and answer questions as you navigate the pipeline.

Office Hours 

Any interested submitters are welcome to join one of the following office hours sessions to connect with the Data Lab team and ask us questions. 

Connect with Us

Potential submitters can join the #scpca-contributions channel in Cancer Data Science Slack to facilitate support from the Data Lab team while preparing their submissions.

You can also reach the Data Lab via email at scpca@ccdatalab.org any time.

Get Started

If you have reviewed the guidelines and are interested in submitting data to the ScPCA Portal, the next step is to complete an intake form to determine the eligibility of your dataset.

After completing the form, you will be contacted by the Data Lab within 3 business days to notify you of your eligibility and provide additional information required for submission. 

Important deadlines for potential submitters to keep in mind:

  • Dataset Submission Deadline: September 1, 2023
  • Application submission deadline (if eligible): September 15, 2023

We hope that you will consider helping us put more pediatric cancer data in the hands of researchers across the globe! Please contact the Data Lab at scpca@ccdatalab.org with any questions.

Update: As of September 2023, we are no longer accepting contributions.

Interested in contributing data to the ScPCA Portal? Sign up to be notified about future opportunities!

In 2019, Alex’s Lemonade Stand Foundation (ALSF) established the Single-cell Pediatric Cancer Atlas (ScPCA) through awards for data generation and to create an atlas of single-cell gene expression profiles of pediatric cancers of different types and from different organ sites. The Data Lab launched the ScPCA Portal in 2022 to make uniformly processed, summarized single-cell and single-nuclei RNA-seq data and de-identified metadata available for download. The ScPCA Portal also supports other data modalities, such as bulk RNA-seq, CITE-seq, and spatial transcriptomics. The ScPCA Portal currently hosts data for over 500 pediatric tumor and patient-derived xenograft samples from more than 50 cancer types, and continues to grow.

Call for Contributions to ScPCA

The Data Lab is seeking contributions to the ScPCA Portal from researchers with existing single-cell datasets. We are now accepting submissions of 10x Genomics single-cell or single-nuclei profiling of childhood and adolescent cancer (ages 0-19) data, broadly defined to include relevant animal models, patient-derived xenografts, or cell lines, as well as tumor data.

Eligible datasets will be made publicly available on the ScPCA Portal. Over 100 users have already downloaded datasets from the portal since it was launched last year! Openly sharing your data can increase the impact of your research, enhance the visibility of your work, and lead to more reproducible research. Researchers that submit data may also be eligible to receive a small one-time grant of unrestricted funds to be used for childhood cancer research.

Eligible researchers must:

To learn more, view the full guidelines for contributing a dataset to the ScPCA Portal.

Support for Potential Contributors

ALSF and the Data Lab look forward to supporting potential contributors through the process of submitting their dataset. 

Awards for Eligible Researchers

Up to 10 eligible researchers will receive $5000 in unrestricted funds. Once an eligible single-cell dataset submission has been completed and approved by the Data Lab, researchers will be invited to complete a grant application for the unrestricted funds consisting of basic contact and payment information. Eligibility will be determined at ALSF’s discretion. Funds are available on a first-come-first-served basis and distributed to the researcher’s institution, which must be a non-profit institution. ALSF does not allow any funds to be used for research utilizing human embryonic stem cells or nonhuman primates. Research with human induced pluripotent stem cells is permissible.

Guidance from the Data Lab

Contributing data to the ScPCA Portal requires potential submitters to generate summarized gene expression data for their samples using the Data Lab’s existing pipeline, which must be completed by September 1, 2023. The Data Lab team is available to provide guidance and answer questions as you navigate the pipeline.

Office Hours 

Any interested submitters are welcome to join one of the following office hours sessions to connect with the Data Lab team and ask us questions. 

Connect with Us

Potential submitters can join the #scpca-contributions channel in Cancer Data Science Slack to facilitate support from the Data Lab team while preparing their submissions.

You can also reach the Data Lab via email at scpca@ccdatalab.org any time.

Get Started

If you have reviewed the guidelines and are interested in submitting data to the ScPCA Portal, the next step is to complete an intake form to determine the eligibility of your dataset.

After completing the form, you will be contacted by the Data Lab within 3 business days to notify you of your eligibility and provide additional information required for submission. 

Important deadlines for potential submitters to keep in mind:

  • Dataset Submission Deadline: September 1, 2023
  • Application submission deadline (if eligible): September 15, 2023

We hope that you will consider helping us put more pediatric cancer data in the hands of researchers across the globe! Please contact the Data Lab at scpca@ccdatalab.org with any questions.

Back To Blog